Early diagnosis is early detection is better prognosis for COVID19

Antibody testing has emerged to be the most effective for presumptive diagnosis of COVID 19. In cases where molecular testing was negative but where there was a strong epidemiological link to COVID-19 infection and paired blood samples (acute and convalescent) showing rising antibody levels.

From detecting effective mechanism to preventing spread of infection

There have been a host of advantages associated to Antibody testing to detect COVID 19. The rapid tests can also be used to detect symptomatic, pre-symptomatic and asymptomatic infectious people before they can spread the coronavirus. As a most effective option, Rapid antigen tests, in addition to their speed, are cheap and easy to produce and therefore more broadly available than the more commonly used gold-standard PCR tests in theory. But these attributes come with a trade-off: less diagnostic accuracy.

Besides this, the rapid tests can be effective in highly controlled settings where people are tested frequently and other mitigation measures are in place. Rapid testing is often necessary to determine eligibility to donate convalescent plasma that has sufficient levels of antibodies, a therapy for COVID-19 to have passive immunization.

Advantage Spring Health Rapid Test Kits

The safety and efficacy of Spring Health has proven benefits, and the overall immune response to the vaccination is high. Individuals with previous exposure should be differentiated in evaluating the response to vaccination. Post vaccination, rapid tests could be used to detect whether and when sufficient immunity has been developed or not. These tests are also useful for determining herd immunity that is important to prevent the spread of infection to the vulnerable segments of the population.

While the current method to detect symptoms involves consultation, lab testing, and getting lab reports, the Rapid Test kits by Spring Health offer several benefits, which include:

-A detection period of 10 minutes

-Easy to operate and handle for the end-users

-No special equipment storage and transportation conditions

-Works equally well with whole blood, serum and plasma

-Tests for 2 antibodies IgM and IgG simultaneously

-Instant Field screening and

-Proven accuracy of over 98%

This gets us back to where we started, wherein it is widely accepted that IgM provides first line defense during viral infections. By providing a generation of adaptive, high affinity IgG responses the rapid tests provide for long-term immunity and immunological memory. Thus, this results in providing accurate information during the stage of infection that can lead to effective prognosis and long-term benefits.

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The Proven Benefits of Antibody Testing for Covid -19

The rapid spread of and severity of Covid-19, scientists and researchers have been aggressive in developing cheap and effective vaccine to combat the virus.

 

 

 

In the year gone by, companies across the globe have developed over 200 vaccines and 40 more are underway for consideration. The question however arises, is how the vaccine works, the know-how of our immune system and treatment of the infected conditions. The types of vaccination may be categorized on the basis of:  1. Using a whole germ 2. Using parts of the germ that triggers the immune system 3. Using the genetic material/part that provides the instructions for making specific proteins.

While most vaccines stimulate the body to make antibodies, some antibody-based tests for coronavirus infection may return a positive result even if you are not, or were not previously infected with the coronavirus. This is called vaccine-induced seropositivity (VISP) test result.

Antibody tests and their functions

In order to establish vaccine efficacy and vaccine-induced immune response, measuring these antibody levels in whole blood, plasma or serum could play a vital role. There are three types of antibodies created in response to infection: IgA, IgG and IgM. IgG is used in most antibody tests as it persists for the longest time and may reflect longer‐term immunity, although it is the last to rise after infection. Many tests assess both IgG and IgM. IgM typically rises quickly with infection and declines soon after an infection is cleared.

Benefits of Antibody testing

There are several advantages of antibody testing against antigen testing. Antibodies test can inform vaccination utilization and status of vaccine response at multiple levels, a) data to establish a threshold for protection or immunity, b) post-vaccination initial response, c) duration of vaccination response. The test that detected IgG is useful to detect herd immunity and previous or recurring infections.

This test detects IgG antibodies that develop in most patients within seven to 10 days after symptoms of COVID-19 begin. Since IgG antibodies remain in the blood after an infection has passed, they can be the key indicators of COVID-19 in the recent past, that can act as a protection against future infection.

It is therefore important to understand that tests to detect antibody responses to COVID-19 in the population will support the development of vaccines. For clinical diagnosis however, such tests have limited utility because they cannot quickly diagnose acute infection to inform actions needed to deter

To enable an effective vaccination strategy, it is an advocate for the use of accessible, automated, high-throughput SARS-CoV-2 serology testing to help confirm the efficacy and promote public health.

About Spring Health rapid test for COVID-19

Spring Health is one of the first companies offering rapid test kits for COVID-19 IgG/IgM. The products fulfil the highest European standards prescribed for European standards, and therefore, carry the CE mark. There are a host of benefits that can be summed up as quick detection, easy to operate for doctors and patients, and works equally and effectively with whole blood, serum and plasma.

 

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